Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture

By Borchelt D.R.  

Human Molecular Genetics, Vol. 7, Iss. 5, 1998-05 ,pp. : 783-790

Oxford University Press

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Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

By Jana Nihar Ranjan   Tanaka Motomasa   Wang Guang-hui   Nukina Nobuyuki  

Human Molecular Genetics, Vol. 9, Iss. 13, 2000-08 ,pp. : 2009-2018

Oxford University Press

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Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis

By Li Shi-Hua   Lam Suzanne   Cheng AnnaL.   Li Xiao-Jiang  

Human Molecular Genetics, Vol. 9, Iss. 19, 2000-11 ,pp. : 2859-2867

Oxford University Press

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

By Faideau Mathilde   Kim Jinho   Cormier Kerry   Gilmore Richard   Welch Mackenzie   Auregan Gwennaelle   Dufour Noelle   Guillermier Martine   Brouillet Emmanuel   Hantraye Philippe   Dglon Nicole   Ferrante Robert J.   Bonvento Gilles  

Human Molecular Genetics, Vol. 19, Iss. 15, 2010-08 ,pp. : 3053-3067

Oxford University Press

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Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

By Benchoua Alexandra   Trioulier Yal   Diguet Elsa   Malgorn Carole   Gaillard Marie-Claude   Dufour Noelle   Elalouf Jean-Marc   Krajewski Stan   Hantraye Philippe   Dglon Nicole   Brouillet Emmanuel  

Human Molecular Genetics, Vol. 17, Iss. 10, 2008-05 ,pp. : 1446-1456

Oxford University Press

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