Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats

By Li S-H.   Li X-J.  

Human Molecular Genetics, Vol. 7, Iss. 5, 1998-05 ,pp. : 777-782

Oxford University Press

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Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

By Jana N.R.   Zemskov E.A.   Wang G-h.   Nukina N.  

Human Molecular Genetics, Vol. 10, Iss. 10, 2001-05 ,pp. : 1049-1059

Oxford University Press

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Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative

By Tebbenkamp Andrew T.N.   Green Cameron   Xu Guilian   Denovan-Wright Eileen M.   Rising Aaron C.   Fromholt Susan E.   Brown Hilda H.   Swing Debbie   Mandel Ronald J.   Tessarollo Lino   Borchelt David R.  

Human Molecular Genetics, Vol. 20, Iss. 14, 2011-07 ,pp. : 2770-2782

Oxford University Press

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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

By Jenkins N.A.  

Human Molecular Genetics, Vol. 8, Iss. 3, 1999-03 ,pp. : 397-407

Oxford University Press

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HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity

By Raychaudhuri Swasti   Sinha Mithun   Mukhopadhyay Debashis   Bhattacharyya Nitai P.  

Human Molecular Genetics, Vol. 17, Iss. 2, 2008-01 ,pp. : 240-255

Oxford University Press

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