Mutations in the gene encoding KRIT1, a Krev-1/rap1a binding protein, cause cerebral cavernous malformations ( CCM1 )

By Sahoo Trilochan   Johnson Eric W.  

Human Molecular Genetics, Vol. 8, Iss. 12, 1999-11 ,pp. : 2325-2333

Oxford University Press

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Interaction between krit1 and icap1 α infers perturbation of integrin β 1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation

By Clatterbuck R.E.  

Human Molecular Genetics, Vol. 10, Iss. 25, 2001-12 ,pp. : 2953-2960

Oxford University Press

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CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis

By Zawistowski Jon S.  

Human Molecular Genetics, Vol. 14, Iss. 17, 2005-09 ,pp. : 2521-2531

Oxford University Press

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A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cells

By Pagenstecher Axel   Stahl Sonja   Sure Ulrich   Felbor Ute  

Human Molecular Genetics, Vol. 18, Iss. 5, 2009-03 ,pp. : 911-918

Oxford University Press

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Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis

By Akers Amy L.   Johnson Eric   Steinberg Gary K.   Zabramski Joseph M.   Marchuk Douglas A.  

Human Molecular Genetics, Vol. 18, Iss. 5, 2009-03 ,pp. : 919-930

Oxford University Press

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