Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture

By Borchelt D.R.  

Human Molecular Genetics, Vol. 7, Iss. 5, 1998-05 ,pp. : 783-790

Oxford University Press

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Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

By Jana Nihar Ranjan   Tanaka Motomasa   Wang Guang-hui   Nukina Nobuyuki  

Human Molecular Genetics, Vol. 9, Iss. 13, 2000-08 ,pp. : 2009-2018

Oxford University Press

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HYPK, a Huntingtin interacting protein, reduces aggregates and apoptosis induced by N-terminal Huntingtin with 40 glutamines in Neuro2a cells and exhibits chaperone-like activity

By Raychaudhuri Swasti   Sinha Mithun   Mukhopadhyay Debashis   Bhattacharyya Nitai P.  

Human Molecular Genetics, Vol. 17, Iss. 2, 2008-01 ,pp. : 240-255

Oxford University Press

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Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease

By Wang Chuan-En   Tydlacka Suzanne   Orr Adam L.   Yang Shang-Hsun   Graham Rona K.   Hayden Michael R.   Li Shihua   Chan Anthony W.S.   Li Xiao-Jiang  

Human Molecular Genetics, Vol. 17, Iss. 17, 2008-09 ,pp. : 2738-2751

Oxford University Press

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Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation

By Havel Lauren S.   Wang Chuan-En   Wade Brandy   Huang Brenda   Li Shihua   Li Xiao-Jiang  

Human Molecular Genetics, Vol. 20, Iss. 7, 2011-04 ,pp. : 1424-1437

Oxford University Press

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