Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design

Author: Perloff E. S.   Mason A. K.   Dehal S. S.   Blanchard A. P.   Morgan L.   Ho T.   Dandeneau A.   Crocker R. M.   Chandler C. M.   Boily N.   Crespi C. L.   Stresser D. M.  

Publisher: Informa Healthcare

ISSN: 1366-5928

Source: Xenobiotica, Vol.39, Iss.2, 2009-02, pp. : 99-112

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