Practical use of the regression offset approach for the prediction of in vivo intrinsic clearance from hepatocytes

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Xenobiotica, Vol. 42, Iss. 9, 2012-09 ,pp. : 841-853

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Evaluation of the human prediction of clearance from hepatocyte and microsome intrinsic clearance for 52 drug compounds

By Sohlenius-Sternbeck A.-K.   Afzelius L.   Prusis P.   Neelissen J.   Hoogstraate J.   Johansson J.   Floby E.   Bengtsson A.   Gissberg O.   Sternbeck J.   Petersson C.  

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Comparison of intrinsic metabolic clearance in fresh and cryopreserved human hepatocytes

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Kinetic determinants of hepatic clearance: Plasma protein binding and hepatic uptake

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In vitro-in vivo correlation for intrinsic clearance for CP-409,092 and sumatriptan: a case study to predict the in vivo clearance for compounds metabolized by monoamine oxidase

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