Author： Yatsenko O. P. Filipenko M. L. Voronina E. N. Khrapov E. A. Sennikov S. V. Kozlov V. A.
Publisher： Springer Publishing Company
ISSN： 0007-4888
Source： Bulletin of Experimental Biology and Medicine, Vol.137, Iss.2, 2004-02, pp. : 179-181
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Abstract
We found an alternative form of mRNA with spliced second exon (IL-4δ2 mRNA) in mouse bone marrow and splenic cells. At rest, the amount of IL-4 mRNA markedly surpassed that of IL-4δ2 mRNA. Stimulation increased the content of both mRNA forms, but the alternative variant is accumulated more intensively and rapidly. We did not detect predominance of IL-4δ2 mRNA over full-lenght mRNA variant in the studied mouse tissues.
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