The Novel One-Pot Synthesis of Functionalized Vinyl Sulfides Using Triphenylphosphine Catalyzed Nucleophilic Addition of Thiols to Acetylenes

Publisher: Bentham Science Publishers

E-ISSN: 1875-6255|4|8|567-570

ISSN: 1570-1786

Source: Letters in Organic Chemistry, Vol.4, Iss.8, 2007-12, pp. : 567-570

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Abstract

3-mercapto-2-butanone undergoes a smooth reaction with electron-deficient symmetric and asymmetric acetylenes in the presence of catalytic amount of triphenylphosphine under neutral conditions to produce S-functionalized vinyl sulfides (Z/E isomers) in moderately high yields.

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