A Green Method for the Synthesis of 3-Substituted Coumarins Catalyzed by L-Lysine in Water Via Knoevenagel Condensation

Publisher: Bentham Science Publishers

E-ISSN: 1875-6255|9|1|19-23

ISSN: 1570-1786

Source: Letters in Organic Chemistry, Vol.9, Iss.1, 2012-01, pp. : 19-23

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Abstract

L-lysine was applied to the synthesis of 3-substituted coumarins through the condensation of various salicylaldehyde with reactive methylene compounds in water. In this work, waste minimization, catalyst recovery, simple operation and easier product work-up were achieved.

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