Molecular modeling of the Trypanosoma brucei aminopurine transporter P2/TbAT1, implicated in resistance to both diamidine and melaminophenyl arsenical classes of drugs, predicts that residues F19 (left), D140 (top) and F316 (right) interact with substrates. The binding site of adenosine (green carbon atoms) and diminazene (yellow carbon atoms) is shown with hydrogen bonds between Asp140 and bound adenosine in dashed blue lines. For details, see the article by Munday et al. on pp. 887–900 of this issue.

Publisher： John Wiley & Sons Inc

E-ISSN： 1365-2958|96|4|i-i

ISSN： 0950-382x

Source： MOLECULAR MICROBIOLOGY, Vol.96, Iss.4, 2015-05, pp. : i-i

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Functional analysis of drug resistance‐associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein

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MOLECULAR MICROBIOLOGY, Vol. 96, Iss. 4, 2015-05 ,pp. : 887-900

John Wiley & Sons Inc

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MOLECULAR MICROBIOLOGY, Vol. 98, Iss. 4, 2015-11 ,pp. : i-i

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In the cyanobacterium Synechocystis sp PCC6803 the repair protease FtsH2 is located in the thylakoid membranes, but has a different distribution from the photosynthetic reaction centers suggesting the existence of dedicated repair zones. False‐color 3D surface plots from fluorescence micrographs show the distribution of fluorescence from chlorophyll (left) and GFP‐tagged FtsH2 (right) in cells grown under low light (top) or high light (bottom). For details, see the article by Sacharz et al. on pp. 448–462 of this issue.

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MOLECULAR MICROBIOLOGY, Vol. 96, Iss. 3, 2015-05 ,pp. : i-i

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MOLECULAR MICROBIOLOGY, Vol. 95, Iss. 3, 2015-02 ,pp. : i-i

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Mutational studies of the xanthine permease XanQ of Escherichia coli, a paradigm for the nucleobase‐cation symporter‐2 (NCS2) family of transporters, identified a critical role for six Gly residues in the gate domain (orange ribbons) and a hydrogen bonding network (inset) involving Gln‐75 (TM2), Asp‐304 (TM9), Thr‐321 (β10) and Gln‐90 (β3) in the core domain. For details, see the article by Karena et al. on pp. 502–517 of this issue.

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MOLECULAR MICROBIOLOGY, Vol. 98, Iss. 3, 2015-10 ,pp. : i-i

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