Author： Lanver Andreas Schmalz Hans-Günther
Publisher： MDPI
E-ISSN： 1420-3049|10|2|508-515
ISSN： 1420-3049
Source： Molecules, Vol.10, Iss.2, 2005-02, pp. : 508-515
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Abstract
An efficient protocol for the amination of 6-chloropurine derivatives through nucleophilic aromatic substitution under microwave irradiation was developed and applied to the synthesis in two steps of a series of new acyclic nucleosides (acyclovir analogues) starting from commercially available compounds.
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