Bisarylureas Based on 1H-Pyrazolo[3,4-d]pyrimidine Scaffold as Novel Pan-RAF Inhibitors with Potent Anti-Proliferative Activities: Structure-Based Design, Synthesis, Biological Evaluation and Molecular Modelling Studies

By Fu Yu   Wang Yuanyuan   Wan Shanhe   Li Zhonghuang   Wang Guangfa   Zhang Jiajie   Wu Xiaoyun  

Molecules, Vol. 22, Iss. 4, 2017-03 ,pp. : 542-542

MDPI

Access to resources Recommend Favorite

Design, Synthesis and Biological Evaluation of 6-(2,6-Dichloro-3,5-dimethoxyphenyl)-4-substituted-1H-indazoles as Potent Fibroblast Growth Factor Receptor Inhibitors

By Zhang Zhen   Zhao Dongmei   Dai Yang   Cheng Maosheng   Geng Meiyu   Shen Jingkang   Ma Yuchi   Ai Jing   Xiong Bing  

Molecules, Vol. 21, Iss. 10, 2016-10 ,pp. : 1407-1407

MDPI

Access to resources Recommend Favorite

Design, Synthesis and the Biological Evaluation of New 1,3-Thiazolidine-4-ones Based on the 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one Scaffold

By Apotrosoaei Maria   Vasincu Ioana Mirela   Dragan Maria   Buron Frédéric   Routier Sylvain   Profire Lenuta  

Molecules, Vol. 19, Iss. 9, 2014-09 ,pp. : 13824-13847

MDPI

Access to resources Recommend Favorite

Novel Anthranilamide-Based FXa Inhibitors: Drug Design, Synthesis and Biological Evaluation

By Wang Wenzhi   Yuan Jing   Fu Xiaoli   Meng Fancui   Zhang Shijun   Xu Weiren   Xu Yongnan   Huang Changjiang  

Molecules, Vol. 21, Iss. 4, 2016-04 ,pp. : 491-491

MDPI

Access to resources Recommend Favorite

Design, Synthesis and Biological Evaluation of Stilbene Derivatives as Novel Inhibitors of Protein Tyrosine Phosphatase 1B

By He Haibing   Ge Yinghua   Dai Hong   Cui Song   Ye Fei   Jin Jia   Shi Yujun  

Molecules, Vol. 21, Iss. 12, 2016-12 ,pp. : 1722-1722

MDPI

Access to resources Recommend Favorite