Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

By Jana N.R.   Zemskov E.A.   Wang G-h.   Nukina N.  

Human Molecular Genetics, Vol. 10, Iss. 10, 2001-05 ,pp. : 1049-1059

Oxford University Press

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Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL

By Kim Sung-Jo   Zhang Zhongjian   Hitomi Emiko   Lee Yi-Ching   Mukherjee Anil B.  

Human Molecular Genetics, Vol. 15, Iss. 11, 2006-06 ,pp. : 1826-1834

Oxford University Press

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Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis

By Sang Tzu-Kang  

Human Molecular Genetics, Vol. 14, Iss. 3, 2005-02 ,pp. : 357-372

Oxford University Press

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Extended polyglutamine repeats trigger a feedback loop involving the mitochondrial complex III, the proteasome and huntingtin aggregates

By Fukui Hirokazu   Moraes Carlos T.  

Human Molecular Genetics, Vol. 16, Iss. 7, 2007-04 ,pp. : 783-797

Oxford University Press

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Polyglutamine protein aggregation and toxicity are linked to the cellular stress response

By Cowan K.J.  

Human Molecular Genetics, Vol. 12, Iss. 12, 2003-06 ,pp. : 1377-1391

Oxford University Press

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