Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease

Author： Chan Edmond Y.W.  

Publisher： Oxford University Press

ISSN： 1460-2083

Source： Human Molecular Genetics, Vol.11, Iss.17, 2002-06, pp. : 1939-1951

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects

By Borchelt D.R.  

Human Molecular Genetics, Vol. 11, Iss. 17, 2002-06 ,pp. : 1927-1937

Oxford University Press

Access to resources Recommend Favorite

Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin

By Wang Hongmin   Lim Precious J.   Vogel Bruce E.   Monteiro Mervyn J.  

Human Molecular Genetics, Vol. 15, Iss. 6, 2006-03 ,pp. : 1025-1041

Oxford University Press

Access to resources Recommend Favorite

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

By Faideau Mathilde   Kim Jinho   Cormier Kerry   Gilmore Richard   Welch Mackenzie   Auregan Gwennaelle   Dufour Noelle   Guillermier Martine   Brouillet Emmanuel   Hantraye Philippe   Dglon Nicole   Ferrante Robert J.   Bonvento Gilles  

Human Molecular Genetics, Vol. 19, Iss. 15, 2010-08 ,pp. : 3053-3067

Oxford University Press

Access to resources Recommend Favorite

Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage

By Kuhn Alexandre   Goldstein Darlene R.   Hodges Angela   Strand Andrew D.   Sengstag Thierry   Kooperberg Charles   Becanovic Kristina   Pouladi Mahmoud A.   Sathasivam Kirupa   Cha Jang-Ho J.   Hannan Anthony J.   Hayden Michael R.   Leavitt Blair R.   Dunnett Stephen B.   Ferrante Robert J.   Albin Roger   Shelbourne Peggy   Delorenzi Mauro   Augood Sarah J.   Faull Richard L.M.   Olson James M.   Bates Gillian P.   Jones Lesley   Luthi-Carter Ruth  

Human Molecular Genetics, Vol. 16, Iss. 15, 2007-08 ,pp. : 1845-1861

Oxford University Press

Access to resources Recommend Favorite

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington’s disease

By Schapira A.  

Human Molecular Genetics, Vol. 10, Iss. 17, 2001-08 ,pp. : 1829-1845

Oxford University Press

Access to resources Recommend Favorite