A sperm survival test and in-vitro fertilization outcome in the presence of male factor infertility.

Author： Coccia M E Becattini C Criscuoli L Fuzzi B Scarselli G

ISSN： 1460-2350

Source： Human Reproduction, Vol.12, Iss.9, 1997-09, pp. : 1969-1973

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Several tests based on semen variables have been proposed to predict the fertilization rate in the presence of male factor infertility, but their significance remains unclear. We investigated the utility of a screening test based on sperm survival (SST) to predict the outcome of in-vitro fertilization (IVF) cycles in the presence of male factor infertility. The SST was considered normal when the percentage of motile spermatozoa 24 h after oocyte insemination was > or =50%. The sperm survival test yielded abnormal results in <90% of="" cycles="" which="" were="" unsuccessful.="" the="" sensitivity="" of="" the="" sst="" was="" 87%="" and="" specificity="" 65%="" with="" a="" positive="" predictive="" value="" of="" 90%="" in="" the="" male="" factor="" group.="" we="" believe="" that="" the="" sst="" may="" be="" a="" useful="" predictor="" of="" the="" ivf="" cycle="" outcome="" and="" we="" propose="" its="" introduction="" into="" the="" routine="" preliminary="" evaluation="" of="" semen="" samples="" in="" cases="" of="" male="" factor="" infertility.="">