Author: Moon Kyung-Suk Lee Hye-Jung Hong Seung-Heon Kim Hyung-Min Um Jae-Young
Publisher: Humana Press, Inc
ISSN: 0895-8696
Source: Journal of Molecular Neuroscience, Vol.32, Iss.2, 2007-05, pp. : 155-159
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Abstract
Cytochrome P450 1A1 (CYP1A1) is involved in the production of arachidonic acid-derived vasoactive substance. We hypothesized that CYP1A1 polymorphism might be related to pathological conditions associated with cerebral infarction (CI). We investigated the effect of genetic polymorphism in the 3′-flanking region (T6235C) of CYP1A1 gene in 353 patients with CI and 376 controls. The distributions of T6235C CYP1A1 genotypes in patients with (TT: 36.0%; TC/CT: 64.0%;
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