Author： Ellis David
Publisher： Taylor & Francis Ltd
ISSN： 0039-7911
Source： Synthetic Communications, Vol.39, Iss.14, 2009-01, pp. : 2585-2595
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Abstract
The conversion of trichloromethyl and tribromomethyltriazoles to the corresponding carboxamide derivatives is described. The trihalomethyl analogs are straightforward to make and react readily with a range of amines to produce carboxamides. The strategy avoids the problems of decarboxylation associated with the use of triazole acids.
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