Author： Hosseinzadeh Rahman Mohadjerani Maryam Tavakoli Rahmatollah Alikarami Mohammad
Publisher： Taylor & Francis Ltd
ISSN： 0039-7911
Source： Synthetic Communications, Vol.40, Iss.2, 2010-01, pp. : 282-288
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Abstract
A convenient catalyst system consisting of copper iodide, L-proline, and potassium fluoride/Al2O3 was effective for the coupling reaction of aryl iodides and bromides with terminal alkynes. In contrast to the conventional Sonogashira reactions, the new procedure is free of palladium and phosphines. Different functionalized aryl halides were coupled with terminal alkynes using this system in good to excellent yields.
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