One-Pot Synthesis of 3,4-Dihydropyridin-2-one via Michael Addition of in situ–Generated Enaminones

Author: Senthil Kumar J. B.   Kumari Neeta   Luthra Pratibha Mehta  

Publisher: Taylor & Francis Ltd

ISSN: 0039-7911

Source: Synthetic Communications, Vol.43, Iss.22, 2013-11, pp. : 3010-3019

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Abstract

Herein we have reported a facile solvent-, catalyst-, and aldehyde-free, one-pot synthesis of 3,4-dihydropyridin-2-one from 1,3-diones using simple and mild reaction conditions. The substrate scope has been also extended to β-ketoesters.[Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications® for the following free supplemental resource: Full experimental and spectral details.]

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