Sites of Interaction of Streptogramin A and B Antibiotics in the Peptidyl Transferase Loop of 23 S rRNA and the Synergism of their Inhibitory Mechanisms

Author： Porse B.T.   Garrett R.A.  

Publisher： Academic Press

ISSN： 0022-2836

Source： Journal of Molecular Biology, Vol.286, Iss.2, 1999-02, pp. : 375-387

Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.

Previous Menu Next

Abstract

Related content

The Donor Substrate Site within the Peptidyl Transferase Loop of 23 S rRNA and its Putative Interactions with the CCA-end of N-blocked Aminoacyl-tRNA

By Porse B.T.   Thi-Ngoc H.P.   Garrett R.A.  

Journal of Molecular Biology, Vol. 264, Iss. 3, 1996-12 ,pp. : 472-483

Academic Press

Access to resources Recommend Favorite

Mutations in the Peptidyl Transferase Center of 23 S rRNA Reveal the Site of Action of Sparsomycin, a Universal Inhibitor of Translation

By Tan G.T.   deBlasio A.   Mankin A.S.  

Journal of Molecular Biology, Vol. 261, Iss. 2, 1996-08 ,pp. : 222-230

Academic Press

Access to resources Recommend Favorite

Mutations at Nucleotides G2251 and U2585 of 23 S rRNA Perturb the Peptidyl Transferase Center of the Ribosome

By Green R.   Samaha R.R.   Noller H.F.  

Journal of Molecular Biology, Vol. 266, Iss. 1, 1997-02 ,pp. : 40-50

Academic Press

Access to resources Recommend Favorite

Resistance Mutations in 23 S rRNA Identify the Site of Action of the Protein Synthesis Inhibitor Linezolid in the Ribosomal Peptidyl Transferase Center

By Kloss P.   Xiong L.   Shinabarger D.L.   Mankin A.S.  

Journal of Molecular Biology, Vol. 294, Iss. 1, 1999-11 ,pp. : 93-101

Academic Press

Access to resources Recommend Favorite

A Sparsomycin-resistant Mutant of Halobacterium salinarium Lacks a Modification at Nucleotide U2603 in the Peptidyl Transferase Centre of 23 S rRNA

By Lazaro E.   Rodriguez-Fonseca C.   Porse B.   Urena D.   Garrett R.A.   Ballesta J.P.G.  

Journal of Molecular Biology, Vol. 261, Iss. 2, 1996-08 ,pp. : 231-238

Academic Press

Access to resources Recommend Favorite