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Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes

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Prediction of differences in in vivo oral clearance of N , N -dipropyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethylamine monohydrochloride (NE-100) between extensive and poor metabolizers from in vitro metabolic data in human liver microsomes lacking CYP2D6 activity and recombinant CYPs

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Prediction of metabolic drug clearance in humans: In vitro–in vivo extrapolation vs allometric scaling

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Prediction of in vivo drug interactions with eplerenone in man from in vitro metabolic inhibition data

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