DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1 gene locus

By Baranello Laura  

Nucleic Acids Research, Vol. 38, Iss. 1, 2010-01 ,pp. : 159-171

Oxford University Press

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The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant

By Fiorani Paola   Chillemi Giovanni   Losasso Carmen   Castelli Silvia   Desideri Alessandro  

Nucleic Acids Research, Vol. 34, Iss. 18, 2006-10 ,pp. : 5093-5100

Oxford University Press

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Human DNA Topoisomerase I: Quantitative Analysis of the Effects of Camptothecin Analogs and the Benzophenanthridine Alkaloids Nitidine and 6-Ethoxydihydronitidine on DNA Topoisomerase I-Induced DNA Strand Breakage

By Holden J.A.   Wall M.E.   Wani M.C.   Manikumar G.  

Archives of Biochemistry and Biophysics, Vol. 370, Iss. 1, 1999-10 ,pp. : 66-76

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Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors

By Cheng Pengfei   Zhu Lingjian   Guo Wei   Liu Wenfeng   Yao Jianzhong   Dong Guoqiang   Zhang Yongqiang   Zhuang Chunlin   Sheng Chunquan   Miao Zhenyuan   Zhang Wannian  

Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 27, Iss. 3, 2012-06 ,pp. : 437-442

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Inhibition of Mg 2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region

By Sorokin Elena P.   Cheng Bokun   Rathi Siddarth   Aedo Sandra J.   Abrenica Maria V.   Tse-Dinh Yuk-Ching  

Nucleic Acids Research, Vol. 36, Iss. 14, 2008-08 ,pp. : 4788-4796

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