An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT₁ Angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies

By Agelis George   Roumelioti Panagiota   Resvani Amalia   Durdagi Serdar   Androutsou Maria-Eleni   Kelaidonis Konstantinos   Vlahakos Demetrios   Mavromoustakos Thomas   Matsoukas John  

Journal of Computer-Aided Molecular Design, Vol. 24, Iss. 9, 2010-09 ,pp. : 749-758

Springer Publishing Company

Access to resources Recommend Favorite

Gaussian mapping of chemical fragments in ligand binding sites

By Wang Kun   Murcia Marta   Constans Pere   Pérez Carlos   Ortiz Angel  

Journal of Computer-Aided Molecular Design, Vol. 18, Iss. 2, 2004-02 ,pp. : 101-118

Springer Publishing Company

Access to resources Recommend Favorite

Structure-based prediction of free energy changes of binding of PTP1B inhibitors

By Wang Jing   Ling Chan Shek   Ramnarayan Kal  

Journal of Computer-Aided Molecular Design, Vol. 17, Iss. 8, 2003-08 ,pp. : 495-513

Springer Publishing Company

Access to resources Recommend Favorite

Struct-NB: predicting protein-RNA binding sites using structural features

By Towfic Fadi   Caragea Cornelia   Gemperline David C.   Dobbs Drena   Honavar Vasant  

International Journal of Data Mining and Bioinformatics, Vol. 4, Iss. 1, 2010-01 ,pp. : 21-43

Inderscience Publishers

Access to resources Recommend Favorite

An efficient motif discovery algorithm with unknown motif length and number of binding sites

By Leung Henry C.M.   Chin Francis Y.L.  

International Journal of Data Mining and Bioinformatics, Vol. 1, Iss. 2, 2006-09 ,pp. : 201-215

Inderscience Publishers

Access to resources Recommend Favorite