Cover Photograph: Hippo signaling controls cell fates in preimplantation mouse embryos. Slightly different mechanisms operate in regulation of Hippo signaling between 16‐cell stage and early blastocyst stage with more than 32 cells. Panels show the confocal images of the 16‐cell (left panel) and early blastocyst (right panel) stage embryos stained with phosphorylated Ezrin/Radixin/Moesin (magenta), a marker for apical domain and cell polarization, and the Hippo pathway coactivator Yap (green). In the early blastocysts, cell position regulates cell polarization through the Par‐aPKC system, and cell polarity controls Hippo signaling. Therefore, all the outer cells are polarized and exhibit nuclear Yap. In contrast, at the 16‐cell stage, Par‐aPKC‐independent mechanism and asymmetric cell division are also involved in regulation of cell polarization. Therefore, some outer cells are apolar and show cytoplasmic Yap.

By  

DEVELOPMENT, GROWTH & DIFFERENTIATION (ELECTRONIC), Vol. 57, Iss. 8, 2015-10 ,pp. : i-i

John Wiley & Sons Inc

Access to resources Recommend Favorite

Role of PKC-dependent pathways in HNE-induced cell protein transport and secretion

By Marinari U.M.   Nitti M.   Pronzato M.A.   Domenicotti C.  

Molecular Aspects of Medicine, Vol. 24, Iss. 4, 2003-08 ,pp. : 205-211

Elsevier

Access to resources Recommend Favorite

EFFECT OF CEPHARANTHINE ON CELL‐TYPE CONVERSION IN B16 MOUSE MELANOMA CELLS

By  

THE JOURNAL OF DERMATOLOGY, Vol. 12, Iss. 2, 1985-04 ,pp. : 138-142

John Wiley & Sons Inc

Access to resources Recommend Favorite

Natural Killer Cell Levels in Older Adult Mice Are Gender-Dependent: Thyroxin Is a Gender-Independent Natural Killer Cell Stimulant

By  

Natural Immunity, Vol. 16, Iss. 4, 1999-06 ,pp. : 165-174

Karger

Access to resources Recommend Favorite

Mechanisms of T Cell Peptide Epitope-Dependent Late Asthmatic Reactions

By  

International Archives of Allergy and Immunology, Vol. 124, Iss. 1-3, 2012-01 ,pp. : 272-275

Karger

Access to resources Recommend Favorite