Vitamin E and hepatotoxic agents

Publisher: Cambridge University Press

E-ISSN: 1475-2662|23|2|297-307

ISSN: 0007-1145

Source: British Journal of Nutrition, Vol.23, Iss.2, 1969-06, pp. : 297-307

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Abstract

1. It has been suggested that carbon tetrachloride damages rat liver by accelerating processes of lipid peroxidation at subcellular sites and that the protective action of vitamin E is due to its functioning as an antioxidant in vivo. Direct evidence for these mechanisms in vivo has been sought and is critically examined.