Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione

Author： Šafarik Jelena Blažević   Koružnjak Jasna Dogan   Karminski-Zamola Grace  

Publisher： MDPI

E-ISSN： 1420-3049|10|1|279-288

ISSN： 1420-3049

Source： Molecules, Vol.10, Iss.1, 2005-01, pp. : 279-288

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Abstract

Some new substituted dihydrothieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones 9-12 and tetrahydrodithieno[2,3-b: 2',3'-d]thieno[2'',3''-c:2'',3''-c’]diquinolin-6,14-dione (17) were prepared from the corresponding new anilides 5-8 and from the corresponding dianilide 15, respectively, by a multistep combination of chemical and photochemical reactions. All the prepared compounds are of particular interest because they might serve as DNA intercalators in anticancer therapy.

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