Author： Tanaka Takuji Tanaka Mayu Tanaka Takahiro Ishigamori Rikako
Publisher： MDPI
E-ISSN： 1422-0067|11|9|3209-3225
ISSN： 1422-0067
Source： International Journal of Molecular Sciences, Vol.11, Iss.9, 2010-09, pp. : 3209-3225
Disclaimer: Any content in publications that violate the sovereignty, the constitution or regulations of the PRC is not accepted or approved by CNPIEC.
Abstract
Colorectal cancer (CRC) is the third most common epithelial malignancy in the world. Since CRC develops slowly from removable precancerous lesions, detection of the lesion at an early stage by regular health examinations can reduce the incidence and mortality of this malignancy. Colonoscopy significantly improves the detection rate of CRC, but the examination is expensive and inconvenient. Therefore, we need novel biomarkers that are non-invasive to enable us to detect CRC quite early. A number of validation studies have been conducted to evaluate genetic, epigenetic or protein markers for identification in the stool and/or serum. Currently, the fecal occult blood test is the most widely used method of screening for CRC. However, advances in genomics and proteomics will lead to the discovery of novel non-invasive biomarkers.
Related content
Genetic and Epigenetic Traits as Biomarkers in Colorectal Cancer
By Berg Marianne Søreide Kjetil
International Journal of Molecular Sciences, Vol. 12, Iss. 12, 2011-12 ,pp. :
Access to resources
Recommend
