Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture

By Borchelt D.R.  

Human Molecular Genetics, Vol. 7, Iss. 5, 1998-05 ,pp. : 783-790

Oxford University Press

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Inhibiting the ubiquitinproteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments

By Li Xiang   Wang Chuan-En   Huang Shanshan   Xu Xingshun   Li Xiao-Jiang   Li He   Li Shihua  

Human Molecular Genetics, Vol. 19, Iss. 12, 2010-06 ,pp. : 2445-2455

Oxford University Press

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Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative

By Tebbenkamp Andrew T.N.   Green Cameron   Xu Guilian   Denovan-Wright Eileen M.   Rising Aaron C.   Fromholt Susan E.   Brown Hilda H.   Swing Debbie   Mandel Ronald J.   Tessarollo Lino   Borchelt David R.  

Human Molecular Genetics, Vol. 20, Iss. 14, 2011-07 ,pp. : 2770-2782

Oxford University Press

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A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

By Roessler Erich  

Human Molecular Genetics, Vol. 14, Iss. 15, 2005-08 ,pp. : 2181-2188

Oxford University Press

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Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats

By Li S-H.   Li X-J.  

Human Molecular Genetics, Vol. 7, Iss. 5, 1998-05 ,pp. : 777-782

Oxford University Press

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