Author： Bao Kai Zhang Weige Zhang Chuanliang Qu Yingwei Tian Liang Wu Lan Zhao Xiang Cheng Maosheng
Publisher： MDPI
E-ISSN： 1420-3049|12|9|2123-2129
ISSN： 1420-3049
Source： Molecules, Vol.12, Iss.9, 2007-08, pp. : 2123-2129
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Abstract
The synthesis of ring-contracted derivatives of erythromycin A via intramolecular transesterification under microwave irradiation of 8,9-anhydro-erythromycin A 6,9-hemiketal and its derivatives is described. It was found that microwave irradiation could significantly improve the yields and shorten the reaction times under either solvent-containing (method A) or solvent-free (method B) conditions.
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