Effects of organic solvents on the time-dependent inhibition of CYP3A4 by diazepam

By Nishiya Y.   Nakamura K.   Okudaira N.   Abe K.   Kobayashi N.   Okazaki O.  

Xenobiotica, Vol. 40, Iss. 1, 2010-01 ,pp. : 1-8

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High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method

By Yamamoto T.   Suzuki A.   Kohno Y.  

Xenobiotica, Vol. 34, Iss. 1, 2004-01 ,pp. : 87-101

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Validation of cytochrome P450 time-dependent inhibition assays: a two-time point IC50 shift approach facilitates kinact assay design

By Perloff E. S.   Mason A. K.   Dehal S. S.   Blanchard A. P.   Morgan L.   Ho T.   Dandeneau A.   Crocker R. M.   Chandler C. M.   Boily N.   Crespi C. L.   Stresser D. M.  

Xenobiotica, Vol. 39, Iss. 2, 2009-02 ,pp. : 99-112

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Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists

By Tang W.   Stearns R. A.   Wang R. W.   Miller R. R.   Chen Q.   Ngui J.   Bakshi R. K.   Nargund R. P.   Dean D. C.   Baillie T. A.  

Xenobiotica, Vol. 38, Iss. 11, 2008-11 ,pp. : 1437-1451

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Method for predicting the risk of drug-drug interactions involving inhibition of intestinal CYP3A4 and P-glycoprotein

By Tachibana T.   Kato M.   Watanabe T.   Mitsui T.   Sugiyama Y.  

Xenobiotica, Vol. 39, Iss. 6, 2009-06 ,pp. : 430-443

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